Confidence Intervals as an Alternative to Significance Testing
نویسنده
چکیده
The article argues to replace null hypothesis significance testing by confidence intervals. Correctly interpreted, confidence intervals avoid the problems associated with null hypothesis statistical testing. Confidence intervals are formally valid, do not depend on apriori hypotheses and do not result in trivial knowledge. The first part presents critique of null hypothesis significance testing; the second part replies to critique against confidence intervals and tries to demonstrate their superiority to null hypothesis significance testing.
منابع مشابه
Measuring Hospital Performance Using Mortality Rates: An Alternative to the RAMR
Background The risk-adjusted mortality rate (RAMR) is used widely by healthcare agencies to evaluate hospital performance. The RAMR is insensitive to case volume and requires a confidence interval for proper interpretation, which results in a hypothesis testing framework. Unfamiliarity with hypothesis testing can lead to erroneous interpretations by the public and other stakeholders. We argue t...
متن کاملMetabolite Parameters as an Appropriate Alternative Approach for Assessment of Bioequivalence of Two Verapamil Formulations
A bioequivalence study of two verapamil formulations (generic verapamil tablets and Isoptin® tablets) was performed by comparing pharmacokinetic parameters of the parent drug and its major metabolite, norverapamil following a single dose administration of 80 mg verapamil hydrochloride in 22 healthy volunteers according to a randomized, two-period, crossover-design study. Moreover, the feasibili...
متن کاملMetabolite Parameters as an Appropriate Alternative Approach for Assessment of Bioequivalence of Two Verapamil Formulations
A bioequivalence study of two verapamil formulations (generic verapamil tablets and Isoptin® tablets) was performed by comparing pharmacokinetic parameters of the parent drug and its major metabolite, norverapamil following a single dose administration of 80 mg verapamil hydrochloride in 22 healthy volunteers according to a randomized, two-period, crossover-design study. Moreover, the feasibili...
متن کاملOn the Logic and Purpose of Significance Testing
There has been much recent attention given to the problems involved with the traditional approach to null hypothesis significance testing (NHST). Many have suggested that, perhaps, NHST should be abandoned altogether in favor of other bases for conclusions such as confidence intervals and effect size estimates (e.g., Schmidt, 1996). The purposes of this article are to (a) review the function th...
متن کاملInterpreting “statistical hypothesis testing” results in clinical research
Difference between "Clinical Significance and Statistical Significance" should be kept in mind while interpreting "statistical hypothesis testing" results in clinical research. This fact is already known to many but again pointed out here as philosophy of "statistical hypothesis testing" is sometimes unnecessarily criticized mainly due to failure in considering such distinction. Randomized cont...
متن کامل